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Ministry Status: Activation Status

Formulary

Exceptional Access Program (EAP)

The Individual Clinical Review process is being phased out and a more streamlined Exceptional Access Program (EAP) has been created to handle requests for drugs that are not listed in the Formulary. For more information please visit the EAP section.

Drug Benefit Prices (DBPs) for products reimbursed under the EAP

Pursuant to section 15 of O.Reg. 201/96 made under the Ontario Drug Benefit Act (ODBA), the Executive Officer (EO) has entered into agreements with manufacturers to establish Drug Benefit Prices (DBPs) for products reimbursed under the Exceptional Access Program (EAP).

For the following products reimbursed under the EAP, the Health Network System (HNS) will adjudicate claims at the DBP listed below.

DIN Trade Name Strength Dosage Form DBP
Effective date November 30, 2020
02465493 Cubicin RF 500mg/Vial Pd for Inj Sol-Vial Pk $184.0000/Vial
Effective date July 31, 2020
02369613 Banzel 100mg Tab $0.7541
02369621 Banzel 200mg Tab $1.5082
02369648 Banzel 400mg Tab $3.2863
02437333 Iclusig 15mg Tab $153.1158
02437341 Iclusig 45mg Tab $349.3847
02484056 Lenvima 4mg/Dose Cap $33.3206
02468220 Lenvima 8mg/Dose Cap $66.6413
02484129 Lenvima 12mg/Dose Cap $99.9619
02450321 Lenvima 10mg Caps Per Dose Daily Dose Pk $73.0857
02450313 Lenvima 14mg Caps Per Dose Daily Dose Pk $114.2847
02450305 Lenvima 20mg Caps Per Dose Daily Dose Pk $171.4374
02450291 Lenvima 24mg Caps Per Dose Daily Dose Pk $228.5694
02247694 Metadol 1mg/mL O/L $0.1258/mL
02241377 Metadol 10mg/mL O/L $0.4545/mL
02247698 Metadol 1mg Tab $0.1929
02247699 Metadol 5mg Tab $0.6363
02247700 Metadol 10mg Tab $1.0541
02247701 Metadol 25mg Tab $1.8541
02459132 Movapo 10mg/mL Inj Sol-Pref Pen 3mL Pk $44.7000/Pref Pen
02322854 Nplate 250mcg/0.5mL Pd for Inj-Vial Pk $1021.7900
02322862 Nplate 500mcg/1mL Pd for Inj-Vial Pk $2043.6000
02463121 Ocaliva 5mg Tab $102.0822
02463148 Ocaliva 10mg Tab $102.0822
02129043 Orgaran 750U/Vial Inj-Vial Pk $26.5200
02372525 OxyNEO 10mg CR Tab $0.9670
09857408 OxyNEO 10mg CR Tab $0.9670
02372533 OxyNEO 15mg CR Tab $1.1680
09857409 OxyNEO 15mg CR Tab $1.1680
02372797 OxyNEO 20mg CR Tab $1.4490
09857410 OxyNEO 20mg CR Tab $1.4490
02372541 OxyNEO 30mg CR Tab $1.9180
09857411 OxyNEO 30mg CR Tab $1.9180
02372568 OxyNEO 40mg CR Tab $2.5030
09857412 OxyNEO 40mg CR Tab $2.5030
09857413 OxyNEO 80mg CR Tab $4.6430
02368153 Xgeva 120mg/1.7mL Inj Sol Vial Pk $635.9200
Effective date: July 22, 2020
02245619 Copaxone 20mg/mL Inj Pref Syr-1mL Pk $47.7000
02245913 Kineret 150mg/mL Inj Pref Syr-0.67mL Pk $51.6557
Effective date July 20, 2020
02481383 Tegsedi 284mg/1.5mL Inj Sol-1.5mL Pref Syr $8.076.9231
Effective date: July 9, 2020
09857395 Avonex Pen 30mcg/0.5mL Pref AutoInj Pen $463.0525
02269201 Avonex PS 30mcg/0.5mL Pref Syr $463.0525
02404508 Tecfidera 120mg DR Cap $17.8511
02420201 Tecfidera 240mg DR Cap $35.7023
02286386 Tysabri 300mg/15mL Inj Sol-15mL Vial Pk $3491.4300
02444402 Plegridy 63mcg/0.5mL & 94mcg/0.5mL Pref Syr-Kit Pk $1771.6000
02444399 Plegridy 125mcg/0.5mL Pref Syr $1771.6000
09857557 Plegridy 63mcg/0.5mL & 94mcg/0.5mL Pref Pen-Kit Pk $1771.6000
09857556 Plegridy 125mcg/0.5mL Pref Pen $1771.6000
Effective date: July 8, 2020
02237319 Rebif 22mcg Inj-Syr Pk $146.4372
02237320 Rebif 44mcg Inj-Syr Pk $178.2722
02318253 Rebif 66mcg Inj-Cart Pk $439.3036
02318261 Rebif 132mcg Inj-Cart Pk $534.8053
Effective date: July 7, 2020
02230845 Flolan 0.5mg/Vial Inj-Vial Pk $19.7400
02230848 Flolan 1.5mg/Vial Inj-5mL Vial Pk $39.4900
02230418 Imitrex Nasal Spray 5mg/Dose Nas Sp-2 Dose Pk $32.2100
02230420 Imitrex Nasal Spray 20mg/Dose Nas Sp $16.5750
02240115 Lamictal 5mg Chew Tab $0.1796
Effective date May 11, 2020
02475472 Radicava 30mg/100mL Inj Sol-2x30mg Bags Pk $920.0000/Pk
Effective date May 6, 2020
02480824 Cabometyx 20mg Tab $293.3300
02480832 Cabometyx 40mg Tab $293.3300
02480840 Cabometyx 60mg Tab $293.3300
Effective date May 1, 2020
02492989 Nucala 100mg/mL Inj Sol-Pref Auto-Injector $1938.4600/Pref Auto-Injector
02492997 Nucala 100mg/mL Inj Sol-Pref Syr $1938.4600/Pref Syr
Effective date April 28, 2020
02470179 Mavenclad 10mg Tab $3212.0000
Effective date April 17, 2020
02461501 Accel-Sevelamer 800mg Tab $1.2634
Effective date March 31, 2020
02292165 Duodopa 20mg/mL & 5mg/mL Intestinal Gel (100mL Cassette) $169.8100
09854785 Humira (Pediatric) 40mg/0.8mL Inj Sol-Vial Pk $785.4500
02424622 Posanol 100mg DR Tab $50.1212
02458039 Venclexta 10mg Tab $7.0000
02458047 Venclexta 50mg Tab $35.0000
02458055 Venclexta 100mg Tab $70.0000
02458063 Venclexta 10mg & 50mg & 100mg Tabs (Starter Kit Pk) $1813.0000/ Kit Pk
Effective date March 4, 2020
02483971 Cresemba 100mg Cap $78.8300
02483998 Cresemba 200mg/Vial Pd for Sol-Vial Pk (Preservative-Free) $400.0000/Vial
Effective date February 26, 2020
02483327 Actemra 162mg/0.9mL Auto-Injector (Preservative-Free) $355.0000/ Auto-Injector
02471574 Velphoro 500mg Chew Tab $4.2036
Effective date January 31, 2020
02298791 Emend 80mg Cap $34.7967
02298805 Emend 125mg Cap $34.7967
Effective date January 22, 2020
02416328 Aubagio 14mg Tab $59.0710
02460521 Kevzara 131.6mg/mL Inj Sol Pref Syr $737.5800/Syr
02460548 Kevzara 175.0mg/mL Inj Sol-Pref Syr $737.5800/Syr
02472961 Kevzara 131.6mg/mL Inj Sol-Pref Pen $737.5800/Pen
02472988 Kevzara 175.0mg/mL Inj Sol-Pref Pen $737.5800/Pen
02469375 Prevymis 240mg Tab $238.7160
02469367 Prevymis 20mg/mL Inj Sol-240mL Vial Pk $238.7160
02469383 Prevymis 480mg Tab $238.7160
02469405 Prevymis 20mg/mL Inj Sol-480mL Vial Pk $469.0910
Effective date January 14, 2020
02397447 Caripul 0.5mg Inj-10mL Vial Pk $17.7800
02397455 Caripul 1.5mg Inj-10mL Vial Pk $35.6500
02478374 Erleada 60mg Tab $29.3370
02434407 Imbruvica 140mg Cap $97.6000
02451158 Uptravi 200mcg Tab $66.4125
02451166 Uptravi 400mcg Tab $66.4125
02451174 Uptravi 600mcg Tab $66.4125
02451182 Uptravi 800mcg Tab $66.4125
02451190 Uptravi 1000mcg Tab $66.4125
02451204 Uptravi 1200mcg Tab $66.4125
02451212 Uptravi 1400mcg Tab $66.4125
02451220 Uptravi 1600mcg Tab $66.4125
02371065 Zytiga 250mg Tab $30.6250
02457113 Zytiga 500mg Tab $61.2500
Effective date November 11, 2019
02484013 Brineura 30mg/mL Inj Sol-5mL Vial Pk $100.6667/mg
Effective date September 12, 2019
02467224 Ocrevus 30mg/mL Inj Sol-10mL Vial Pk (Preservative Free) $8150.0000/Vial
Effective date August 26, 2019
02272199 Somavert 10mg Pd for Inj-Vial Pk $118.9800/Vial
02272202 Somavert 15mg Pd for Inj-Vial Pk $178.4700/Vial
02272210 Somavert 20mg Pd for Inj-Vial Pk $237.9600/Vial
02448831 Somavert 25mg Pd for Inj-Vial Pk $297.4500/Vial
02448858 Somavert 30mg Pd for Inj-Vial Pk $356.9400/Vial
Effective date August 14, 2019
02473569 Kisqali 200mg Tab $84.6500
Effective date June 28, 2019
02415666 Giotrif 20mg Tab $76.6354
02415674 Giotrif 30mg Tab $76.6354
02415682 Giotrif 40mg Tab $76.6354
02443066 Ofev 100mg Cap $28.4168
02443074 Ofev 150mg Cap $56.8336
Effective date June 13, 2019
02473232 Fasenra 30mg/mL Inj Sol-Pref Syr (Preservative Free) $3876.9200/Syr
Effective date May 31, 2019
02454408 Lynparza 50mg Cap $16.4665
02475200 Lynparza 100mg Tab $65.8925
02475219 Lynparza 150mg Tab $65.8925
Effective date May 13, 2019
02468042 Galafold 123mg Cap $1700.0000
02427184 Vimizim 5mg/5mL Inj Sol-5mL Vial Pk (Preservative Free) $1091.0900/Vial
Effective date April 30, 2019
02419149 Bosulif 100mg Tab $38.9787
02452340 Cotellic 20mg Tab $125.1025
02409267 Erivedge 150mg Cap $313.1904
02393751 Esbriet 267mg Cap $13.6251
02464489 Esbriet 267mg Tab $13.4240
02464500 Esbriet 801mg Tab $40.2720
02337819 Extavia 0.3mg Pd for Inj - Vial $103.8640
02247725 Fuzeon 108mg/Vial Inj-3mL Vial Pk $42.3230
09857447 Gleevec 100mg Tab $29.7475
09857448 Gleevec 400mg Tab $118.9900
02389630 Inlyta 1mg Tab $19.8924
02389649 Inlyta 5mg Tab $99.4621
02388006 Jakavi 5mg Tab $86.6275
02388014 Jakavi 15mg Tab $86.6275
02388022 Jakavi 20mg Tab $86.6275
02434814 Jakavi 10mg Tab $86.6275
02409623 Mekinist 0.5mg Tab $76.9840
02409658 Mekinist 2mg Tab $307.9380
02177757 M-Eslon 200mg ER Cap $4.2960
09857573 M-Eslon 200mg ER Cap $4.2960
02376393 Nutropin AQ NuSpin 10 10mg/2mL Inj Disposable-Pen $407.4200
02399083 Nutropin AQ NuSpin 20 20mg/2mL Inj Sol-20mg Cart Pk $814.8400
02399091 Nutropin AQ NuSpin 5 5mg/2mL Inj Sol-5mg Cart Pk $203.7100
02248077 Pegasys 180mcg/0.5mL Pref Syr-0.5mL Pk $419.7000
02046733 Pulmozyme 1mg/mL Inj-2.5mL Pk $40.7397
02241927 Rituxan 10mg/mL Inj-10mL Vial Pk $482.3050/Vial
09857407 Rituxan 10mg/mL Inj-50mL Vial Pk $2411.5400/Vial
02409607 Tafinlar 50mg Cap $44.8775
02409615 Tafinlar 75mg Cap $67.3165
02326442 Tykerb 250mg Tab $24.6410
02286386 Tysabri 300mg/15mL Inj Sol-15mL Vial Pk $3374.9900
02352303 Votrient 200mg Tab $36.0805
02260565 Xolair 150mg Inj Pd-6mL Vial Pk $635.2000/Vial
02380242 Zelboraf 240mg Tab $35.5539
Effective date April 17, 2019
02458136 Alecensaro 150mg Cap $42.1666
Effective date April 10, 2019
02418320 Lemtrada 12mg/1.2mL Inj Sol-12mg/1.2mL Vial $1085.9258/mg
Effective date March 28, 20199
02293404 Posanol 40mg O/L $9.7371
Effective date February 4, 2019
02442302 Quinsair 100mg/mL Inh Sol-2.4mL Amp
(Preservative Free)
$64.4887/amp
December 12, 2018
02445727 Revestive 5mg Vial Pd for Inj-Vial Pk $904.0000/Vial
Effective date November 20, 2018
02465663 Spinraza 2.4mg/mL Inj Sol-5mL Vial Pk $9833.3333/mg
Effective date October 29, 2018
02457857 Hemangiol 3.75mg/mL Oral Sol $2.2808
Effective date October 11, 2018
02466236 Rydapt 25mg Cap $167.9248
02436779 Zykadia 150mg Cap $52.0000
Effective date October 3, 2018
02459418 Revlimid 2.5mg Cap $329.5000
02456214 Tagrisso 40mg Tab $294.6764
02456222 Tagrisso 80mg Tab $294.6764
Effective date September 27, 2018
02453150 Ibrance 75mg Cap $253.9123
02453169 Ibrance 100mg Cap $253.9123
02453177 Ibrance 125mg Cap $253.9123
Effective date September 13, 2018
02378582 Caprelsa 100mg Tab $99.1573
02378590 Caprelsa 300mg Tab $198.3150
Effective date June 29, 2018
02329840 Cayston 75mg/vial Pd Inh Sol- Vial Pk $42.3989
Effective date June 6, 2018
02444615 Strensiq 18mg/0.45mL Single Use Vial $1358.6400
02444623 Strensiq 28mg/0.7mL Single Use Vial $2113.4400
02444631 Strensiq 40mg/1mL Single Use Vial $3019.2000
02444658 Strensiq 80mg/0.8mL Single Use Vial $6038.4000
Effective date April 30, 2018
02412764 Adempas 0.5mg Tab $43.7200
02412772 Adempas 1mg Tab $43.7200
02412799 Adempas 1.5mg Tab $43.7200
02412802 Adempas 2mg Tab $43.7200
02412810 Adempas 2.5mg Tab $43.7200
02368250 Tasigna 150mg Cap $29.7800
02315874 Tasigna 200mg Cap $41.4575
Effective date April 19, 2018
02460351 Ilaris 150mg/mL Inj Sol-Vial Pk $106.6667 per mg
02282097 Orencia 250mg/Vial Inj Pd-Vial Pk $500.3411
02402475 Orencia
(Preservative Free)
125mg/mL Inj Sol-Pref Syr-1mL Pk $373.7881
Effective date April 9, 2018
02453304 Ravicti 1.1g/mL Oral Liquid $48.0000
Effective date March 15, 2018
02449781 Nucala 100mg/mL Inj Pd-Vial Pk $1938.4600
Effective date January 31, 2018
02465574 Cimzia 200mg/mL Inj Sol – Pref Pen $664.5100
Effective date November 30, 2017
02436523 Ferriprox 100mg/mL Oral Solution $3.1900/mL
02436558 Ferriprox 1000mg Tab $31.8800
Effective date May 31, 2017
02384256 Xalkori 200mg Tab $130.0000
02384264 Xalkori 250mg Tab $130.0000
02428393 Sodium Thiosulfate Injection USP 250mg/mL Inj Sol-50mL Vial Pk $130.0000
Effective date April 27, 2017
02350092 Actemra 80mg/4mL Inj Sol-Vial Pk $182.8000
02350106 Actemra 200mg/10mL Inj Sol-Vial Pk $457.0000
02350114 Actemra 400mg/20mL Inj Sol-Vial Pk $914.0000
02424770 Actemra 162mg/0.9mL Inj Sol-Pref Syr $358.9050
02419157 Bosulif 500mg Tab $152.2403
02361825 Revolade 25mg Tab $65.0000
02361833 Revolade 50mg Tab $130.0000
Effective date April 18, 2017
02436841 Entyvio 300mg Inj Sol-Vial $3290.0000
Effective date March 28, 2017
02386666 Seacalphyx 250mg/mL Inj Sol $2.7500/mL
Effective date March 14, 2017
02440601 Revlimid 20mg Cap $403.0000
Effective date November 30, 2016
02443651 pH 12 Sterile Diluent for Flolan 94mg/73.3mg/50mL Vial Inj Sol-50mL Vial Pk $10.6450
Effective date October 19, 2016
02438798 Zydelig 100mg Tab $85.3500
02438801 Zydelig 150mg Tab $85.3500
Effective date September 16, 2016
02413175 Simponi 100mg/1.0mL Pre-Filled Syringe $1555.1700
02413183 Simponi 100mg/1.0mL Auto-Injector $1555.1700
Effective date April 29, 2016
02240325 Xenical 120mg Cap $1.6574
02407329 Xtandi 40mg Tab $29.1954
Effective date January 28, 2016
02387174 Dificid 200mg Tab $94.60
02324784 Simponi 50mg/0.5mL Auto-Injector $1,555.17
02324776 Simponi 50mg/0.5mL Pre-Filled Syringe $1,555.17
Effective date November 5, 2015
02425696 Firazyr 30mg/3mL Pre-filled syringe $2,700.0000
Effective date July 10, 2015
02334852 Norditropin Nordiflex 5mg/1.5mg Inj Sol-Pref Pen $194.7000
02334860 Norditropin Nordiflex 10mg/1.5mg Inj Sol-Pref Pen $389.4000
02334879 Norditropin Nordiflex 15mg/1.5mg Inj Sol-Pref Pen $584.1000
Effective date June 22, 2015
02398958 Diacomit 250mg Cap $5.8984
02398966 Diacomit 500mg Cap $11.7783
02398974 Diacomit 250mg/Pk Pd for Oral Susp $5.8984
02398982 Diacomit 500mg/Pk Pd for Oral Susp $11.7783
Effective date February 26, 2015
02403390 Stivarga 40mg Tab $72.6200
Effective date February 6, 2015
02419580 Pomalyst 1mg Cap $500.0000
02419599 Pomalyst 2mg Cap $500.0000
02419602 Pomalyst 3mg Cap $500.0000
02419610 Pomalyst 4mg Cap $500.0000
Effective date July 6, 2014
02401703 Genotropin Go Quick 5.3mg powder for solution Pre-filled pen $147.8700
02401711 Genotropin Go Quick 12mg powder for solution Pre-filled pen $334.8000
02401762 Genotropin MiniQuick 0.6mg powder for solution Prefilled syringe $16.7400
02401770 Genotropin MiniQuick 0.8mg powder for solution Prefilled syringe $22.3200
02401789 Genotropin MiniQuick 1.0mg powder for solution Prefilled syringe $27.9000
02401797 Genotropin MiniQuick 1.2mg powder for solution Prefilled syringe $33.4800
02401800 Genotropin MiniQuick 1.4mg powder for solution Prefilled syringe $39.0600
02401819 Genotropin MiniQuick 1.6mg powder for solution Prefilled syringe $44.6400
02401827 Genotropin MiniQuick 1.8mg powder for solution Prefilled syringe $50.2200
02401835 Genotropin MiniQuick 2.0mg powder for solution Prefilled syringe $55.8000
Effective date June 20, 2014
02397412 Kalydeco 150mg Tab $420.0000
Effective date May 2, 2014
00745626 Humatrope 1mg / mL 5mg Vial $233.3500
02243077 Humatrope 3.15mL 6mg Cartridge $280.0200
02243078 Humatrope 3.15mL 12mg Cartridge $560.0400
02243079 Humatrope 3.15mL 24mg Cartridge $1,120.0800
Effective date April 16, 2014
02371553 Incivek 375mg Tab $69.3810
Effective date January 30, 2014
02244016 Remicade 100mg/10mL Injection $987.5600
02284227 Nexavar 200mg Tab $46.4689
02280795 Sutent 12.5mg Cap $64.4157
02280809 Sutent 25mg Cap $128.8303
02280817 Sutent 50mg Cap $257.6610
Effective date April 30, 2013
02215136 Saizen 3.33mg Inj Pd-3.33mg Vial Pk with diluent $149.2500
02237971 Saizen 5mg Inj Pd-5mg vial Pk with Diluent $224.0500
02272083 Saizen 8.8mg Inj Pd-8.8mg Vial Pk $358.4700
02350122 Saizen 6mg/Cart (5.83mg/mL) Inj Cart $268.8300
02350130 Saizen 12mg/Cart (8mg/mL) Inj Cart $537.6600
02350149 Saizen 20mg/Cart (8mg/mL) Inj Cart $896.1000
Effective date February 20, 2013
02350580 Kuvan 100mg Tab $33.0000
Effective date September 13, 2012
02355191 Thalomid 50mg Cap $29.4690
02355205 Thalomid 100mg Cap $58.9380
02355221 Thalomid 200mg Cap $117.8800
Effective date August 27, 2012
02325063 Omnitrope 5mg/1.5mL Inj-5mg Pen Cart Pk $155.8000
02325071 Omnitrope 10mg/1.5mL Inj-10mg Pen Cart Pk $311.6000
Effective date March 19, 2012
02344939 Ilaris 150mg Powder for solution for sc injection (vial) $106.6667/mg
Effective date October 27, 2011
02357119 Vpriv® 400U Vial $1955.0000
Effective date September 30, 2010
02331675 Cimzia 200mg/mL Pre-Filled Syringe $664.5100
Effective date October 8, 2009
02169649 Betaseron Inj Pref Syr - 0.3mg Injection $110.0000
Effective date July 22, 2009
02317699 Revlimid 15mg Cap $382.0000
02317710 Revlimid 25mg Cap $424.0000
Effective date June 11, 2009
02284863 Myozyme 50mg/vial Lyophylized Powder $840.3100
Effective date May 27, 2009
02296314 Elaprase 2mg/mL 3mL Vial $3,800.00
Effective date January 19, 2009
02304899 Revlimid 5mg Capsule $340.0000
02304902 Revlimid 10mg Capsule $361.0000

Until further notice, for all other products reimbursed under the EAP, pharmacies will continue to be reimbursed their acquisition cost plus the applicable mark-up:

  • 8% when the total drug cost is less than $1,000.00;
  • 6% when the total drug cost is greater than or equal to $1,000.00.

See also:

For More Information

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