Bulletin

Bulletin Number
        4352
Date
        May 9, 2000
Direct inquiries to

         Ministry of Health
         Processing Office


(address below)
Distribution
       Physicians, Hospitals, Clinics, Laboratories
Subject      Provincial Predictive Genetic Testing Service for Hereditary Breast, Ovarian and Colon Cancers
The Ministry of Health and Long-Term Care is pleased to announce the expansion of services at the Provincial Regional Genetics Program (PRGP) to include genetic counselling and testing for patients who may have a predisposition to hereditary breast, ovarian, and colon cancers.

Beginning April 19, 2000, predictive genetic counselling and testing will be offered at the PRGP's nine regional centres in Downtown Toronto, North Toronto, Oshawa, Mississauga, Hamilton, London, Ottawa, Kingston and Sudbury. For patients determined to be at increased risk of inherited cancer, services provided will include genetic counselling, risk assessment, genetic testing and referral for follow-up services.

To assist with the implementation of this new provincial service, the ministry will establish an Implementation Steering Committee with the assistance of the PRGP. Criteria for selection of appropriate patients to be referred to this service will be distributed to physicians in the near future.Information for the public will also be developed for province wide dissemination. Accompanying this bulletin is a FACT sheet for the public that will also be posted on the Ministry of Health and Long-Term Care's website. (www.health.gov.on.ca)

A Provincial Advisory Committee on Predictive Genetic Testing Services will also be established to develop guidelines, principals and broad criteria for the introduction of other new genetic services in the province.

Background:

Although up to 20 per cent of women in the general population have a family history of breast cancer, less than five percent are at high risk for hereditary breast cancer. Certain features in the family history may suggest increased risk. A detailed family history can identify potential breast cancer gene (BRCA1 and BRCA2) mutation carriers. Women identified as carriers have a substantially increased risk of breast and ovarian cancer. It is also possible through genetic testing to identify individuals at risk of developing hereditary nonpolyposis colon cancer (HNPCC) and familial adenomatous polyposis (FAP).

Early detection of a person's genetic predisposition to inherited breast, ovarian or colon cancer, can lead to medical interventions and surveillance that will significantly reduce the risk of these people developing the disease or improve outcomes through early diagnosis.

Office locations
Barrie
30 Poyntz St.
L4M 3P2
Hamilton
119 King St. W
P.O. Box 2280, Stn. A
L8N 4C8
Kenora
220-808 Robertson St.
P9N 1X9
Kingston
1055 Princess St.
P.O. Box 9000
K7L 5A9
Kitchener
1400 Weber St. E. Unit B2
N2A 3Z8
London
217 York St., 5th FloorP.O. Box 5700
Terminal A
N6A 1B7
Mississauga
201 City Centre Dr.
P.O. Box 7020, Stn. A
L5A 3M1
North Bay
101-447 McKeown St.
P1B 9S9
Oshawa
Exec. Tower,
Oshawa Centre.
419 King St. W.
P.O. Box 635 L1H 8L4
Ottawa
Fuller Building
75 Albert Street
K1P 5Y9
Owen Sound
981 2nd Avenue E.
N4K 2H5
Peterborough
550 Lansdowne St. W.
K9J 8J8
St. Catharines
59 Church St
3rd Floor
L2R 3C3
Sarnia
452 Christina St. N.
N7T 5W4
Sault Ste. Marie
Roberta Bondar Place
70 Foster Dr., Ste. 100
P6A 6V4
Sudbury
199 Larch St.,
Suite 801
P3E 5R1
Thunder Bay
435 James St. S. ,
Suite 113
P7E 6T1
Timmins
38 Pine St. N., Ste. 110
P4N 6K6
Toronto
2195 Yonge St.
P.O Box 1700 Stn. A
M5W 1G9
Windsor
1427 Ouellette Ave.
N8X 1K1
Head Office
P.O. Box 48
Kingston, ON
K7L 5J3